Week 2 fantasy and betting guide spotlights a slate rich in NFC/DIV rivalries, a short-week test for Washington in Green Bay, and a QB swap that could shift SF’s fantasy landscape. Jayden Daniels’ multi‑dimensional presents a new stress test for the Packers’ front, while the Rams’ pass rush and a banged‑up SF offense shape a few must‑buy and fade calls for fantasy lineups and prop bets.

Key matchups loom: Bills at Jets, Bengals at Jaguars, and a Bucs‑Texans clash that leans defense and run game. The latest injury news—Purdy’s turf toe and Jones’ Indy resurgence—could tilt Week 2 upside toward explosive receivers and run‑heavy schemes. Managers should lean into high‑volume roles, monitor QBs’ health, and target offenses with clear functional roles in favorable spots.

Bottom line for fantasy: chase safe volume in the games expected to stay competitive, target matchup-advantaged receivers, and be ready to pivot on late-week injury news. Week 2 offers multiple opportunities to deploy mid-round values and streaming options with clear upside in primetime and Sunday slots.

Calvin Austin flashed Week 1 as Pittsburgh’s clear WR2, snagging 4 of 6 targets for 70 yards and a TD. Week 2 pits the Steelers against Seattle’s stout secondary, and Pittsburgh’s plan to lean on defense and the run could cap passing volume. With the 39.5-point total, Austin’s Week 2 fantasy ceiling appears limited, making him a shaky start in most leagues and a better hold in deeper formats where upside might still exist.

Talanoa Hufanga set the tone in his Broncos debut, piling up a game-high 11 tackles and forcing a fumble as Denver throttled Tennessee. His range, blitz instincts, and leadership sparked a defensive surge that coaches say is contagious. The performance hints at a top-tier floor for IDP fantasy managers and a rising ceiling for Denver’s unit as the season unfolds.

Fantasy takeaway: Hufanga’s playmaking should lift defensive scoring for Denver and raise his own IDP upside, especially if he stays unleashed as a versatile chess piece in this scheme.